We would like to inform you that from 18.2.2022 a new, Real-time PCR test is available to determine the genetic predisposition to the development of celiac disease (gluten-enteropathy).
Celiac disease is an autoimmune disease (also called enteropathy), which is characterized by gluten intolerance. It is also defined as a multifactorial disease with a strong genetic component. Genetic susceptibility to celiac disease involves the presence of HLA-DQ2 / HLA-DQ8 heterodimers, which play a key role in the pathogenesis of the disease by activating the immune response. In 90-95% of patients with celiac disease there is expression of the HLA-DQA1 * 05 / DQB1 * 022 heterodimer.
A highly sensitive molecular test for genetic predisposition to celiac disease is available at Avicenna Laboratory by DNA analysis isolated from a patient’s blood.
The test is based on RT PCR technology for fast and accurate identification of HLA class II – specific for celiac disease.
– diagnostic test that helps diagnose celiac disease.
– this test is especially important in cases where there are discrepancies between serological blood tests and / or intestinal biopsy.
– genetic testing is also used to identify people predisposed to celiac disease, especially in high-risk groups, such as first-degree relatives of people with celiac disease.
– patients with other autoimmune diseases (type I diabetes, thyroiditis and multiple sclerosis) or genetic diseases (Down syndrome, Turner syndrome or Williams syndrome).
Sample: venous blood
Price: 4950 denars
The results are ready in just one working day