DiabeGene – test for determining genetic predisposition and risk of Type 1 Diabetes
Diabetes mellitus type 1 is the most common form of diabetes in children and adults.
It is a disease that affects the body’s ability to convert glucose from food into energy. In most cases, type 1 diabetes develops early in life and is often diagnosed during childhood.
The disease begins when the immune system attacks the insulin-producing cells in the pancreas and is characterized by subtotal (> 80%) or complete destruction of pancreatic cells (the beta cells of the pancreatic islets of Langerhans), caused by an autoimmune reaction (lymphocytic insulitis). The pancreas does not produce insulin or produces very little insulin, and therefore these patients are dependent on insulin.
Genetics of type 1 diabetes mellitus
Genetic predisposition plays a very important role in the etiology of type 1 diabetes. By determining certain genes (variants of HLA alleles), it is possible to determine what the genetic predisposition is and how likely a person is to develop type 1 diabetes. This test can be useful. a tool for identifying individuals (children and teenagers), who are at risk of developing type 1 diabetes, in order to make a good plan for monitoring their condition. In addition, the test not only makes risk stratification (medium or high risk), but it also provides information on whether there is a genetic combination that has a “protective” role for the organism against the occurrence of the disease.
Price of the test: 6850 MKD
Available without an appointment in all laboratories of Avicena Laboratory.
Sample required: blood
Issuance of results in 1 working day.