A highly sensitive molecular test for genetic fructose intolerance is available at Avicena Laboratory. The test detects mutations in genes responsible for Aldolase B deficiency, which is involved in the metabolism of fructose, sucrose and sorbitol.
Sample needed: whole blood
Price: 3000 MKD
Fructose is a sugar naturally found in fruits, fruit juices, honey and some plants. Fructose is also a key component of the common white sugar . In addition, corn syrup, which is used to sweeten processed foods and beverages, is high in fructose.
When the digestive system does not properly absorb fructose, symptoms of fructose intolerance can occur.
Hereditary fructose intolerance is a genetic disorder. If the body lacks the necessary proteins or enzymes important for the breakdown of fructose, we talk about fructose intolerance. This means that the body can not process fructose which is found in many different foods.
This type of fructose intolerance occurs when the enzyme aldolase B is dysfunctional. This enzyme is found in the liver and helps convert fructose into useful energy. There is a 25% chance that a person will develop hereditary fructose intolerance if both parents have a gene that causes a malfunctioning aldolase B enzyme.
People with fructose intolerance should limit their intake of foods high in fructose. If a person with fructose intolerance eats foods that contain fructose or sucrose, the body cannot convert sugar into glucose, and it accumulates in the body and can cause damage to the liver and kidneys.
There is also fructose intolerance, known as fructose malabsorption. This condition is not caused by an enzyme deficiency. The cells in the gut simply cannot break down fructose into the food we eat.
Learn more about fructose intolerance on this link.